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2019 Vol. 28, No. 11
Published: 01 December 2019

Original articles
 
       Original articles
749 Membrane binding of the pH sensitive antimicrobial peptide LAH4 studied by EPR spectroscopy Hot!
Yina Sheng, Shenlin Wang, Guoquan Liu
DOI: 10.5246/jcps.2019.11.071
2019 Vol. 28 (11): 749-759 [Abstract] ( 28 ) HTML (114 KB)  PDF (1406 KB)  ( 86 )
760 Engineering the protein targeting two pathways of cerebral ischemia reperfusion injury provides better neuroprotective effect than targeting one pathway Hot!
Kuai Yu, Ruyi Li, Yuanjun Zhu, Xiaoyan Liu, Yinye Wang
DOI: 10.5246/jcps.2019.11.072
2019 Vol. 28 (11): 760-769 [Abstract] ( 22 ) HTML (99 KB)  PDF (1603 KB)  ( 65 )
770 Construction of a phage displayed library based on a lipocalin scaffold and preliminary screening of anticalins with specificity for the FcεRI-α receptor Hot!
Hua Peng, Jinkui Ma, Jie Cheng, Chengzhi Huang, Hongbin Zhang
DOI: 10.5246/jcps.2019.11.073
2019 Vol. 28 (11): 770-777 [Abstract] ( 15 ) HTML (88 KB)  PDF (1272 KB)  ( 68 )
778 Apatinib induces apoptosis of breast cancer cells by redistribution of Fas into lipid rafts Hot!
Shunchao Yan, Xin Jiao, Na Li, Yangfan Du, Chengyao Jiang
DOI: 10.5246/jcps.2019.11.074
2019 Vol. 28 (11): 778-785 [Abstract] ( 26 ) HTML (76 KB)  PDF (1633 KB)  ( 65 )
786 Synthesis and biological evaluation of indeno[1, 2-b]indole derivatives as dual topoisomerase I & II inhibitors: novel multidrug resistant reversal anticancer agents Hot!
Dongbo Lu, Yu Chen, Shan Liu, Chao Guo, Xia Li, Zhongjun Li, Xiangbao Meng
DOI: 10.5246/jcps.2019.11.075
2019 Vol. 28 (11): 786-801 [Abstract] ( 24 ) HTML (214 KB)  PDF (1600 KB)  ( 84 )
802 An established LC-MS/MS method and a developed PK model for the study of pharmacokinetic properties of benapenem in infected mice Hot!
Xiwei Ji, Zisheng Kang, Yun Li, Xiping Yang, Xifeng Ma, Chongtie Shi, Yuan Lv
DOI: 10.5246/jcps.2019.11.076
2019 Vol. 28 (11): 802-811 [Abstract] ( 28 ) HTML (95 KB)  PDF (1580 KB)  ( 68 )
812 Simultaneous determination of the pharmacokinetics of the active components of San-Chen-pill by UPLC-Q-Exactive-MS Hot!
Lingling Zhang, Huiwen Zhang, Shikui Wu, Hong Liu, Jingyuan Li, Xin Dong, Huimin Xia, Huanyun Wang
DOI: 10.5246/jcps.2019.11.077
2019 Vol. 28 (11): 812-824 [Abstract] ( 23 ) HTML (110 KB)  PDF (5234 KB)  ( 94 )
  News
· The team of Professor Qiang Zhang has made a series of progress in the field of targeted drug delivery in 2020 new
· Professor Tao Liu secured the Outstanding Youth Science Foundation of Beijing Natural Science Foundation in 2020 new
· Professor Ning Jiao won the Natural Science First Prize of Beijing Science and Technology Award new
· The team of Professor Xinshan Ye has made progress in stereoselective electroglycosylation new
· The group of Yiguang Wang created a new intelligent nano delivery technology in programmed response to tumor molecular signals
· The group of Xinjing Tang developed a novel light-sensitive CRISPR-Cas9 System to realize the light regulation of gene editing
· The group of Suwei Dong created a new strategy to simulate complex polysaccharides using self-assembled peptides
· The group of Prof. Xianrong Qi have provided a new delivery strategy for accurate diagnosis and treatment of glioma
· The group of Prof. Yanxing Jia have realized the first total synthesis of natural product (-)-glaucocalyxin A
· Tao Liu research group of Peking University School of Pharmaceutical Sciences and Mo Li research group of Peking University Third Hospital joint developed CRISPR non-natural amino acid coupling technique to improve the efficiency of precise genome editing
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