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2018 Vol. 27, No. 7
Published: 25 July 2018

Original articles
Drug administration and clinical pharmacy column
 
       Original articles
451 Designing natural product-like virtual libraries using deep molecule generative models Hot!
Yibo Li, Xin Zhou, Zhenming Liu, Liangren Zhang
DOI: 10.5246/jcps.2018.07.046
2018 Vol. 27 (7): 451-459 [Abstract] ( 68 ) HTML (74 KB)  PDF (1343 KB)  ( 189 )
460 Development of palladium-catalyzed Suzuki carbonylation reaction without external ligand and its application in modification of novel series of α7 nAChR PAMs Hot!
Ying Meng, Wenxing Zou, Zongze Huang, Xintong Wang, Wenxuan Jiao, Wenjun Xie, Xiling Bian, KeWei Wang, Qi Sun
DOI: 10.5246/jcps.2018.07.047
2018 Vol. 27 (7): 460-468 [Abstract] ( 49 ) HTML (119 KB)  PDF (1358 KB)  ( 63 )
469 Similar pyridinone compounds with different activities of anti-HIV-1 reverse transcriptase Hot!
Yunqi Liu, Xixi Li, Xiaodong Dou, Chao Tian, Zhili Zhang, Junyi Liu, Xiaowei Wang
DOI: 10.5246/jcps.2018.07.048
2018 Vol. 27 (7): 469-477 [Abstract] ( 62 ) HTML (119 KB)  PDF (1449 KB)  ( 57 )
478 Construction of a Caco-2/EAhy926 cell tandem compound model and its application in mechanism study of nanoparticle transcytosis Hot!
AnPu Yang, Bei Wei, Jiafang Song, Xiangfu Guo, Yuxi Cheng, Bing He, Hua Zhang, Xueqing Wang, Qiang Zhang
DOI: 10.5246/jcps.2018.07.049
2018 Vol. 27 (7): 478-489 [Abstract] ( 50 ) HTML (109 KB)  PDF (1765 KB)  ( 49 )
490 Preparation and characterization of intestinal transporter-targeted polymeric micelles Hot!
Chuyu He, Yao Jin, Yunqiang Deng, Yang Zou, Shidi Han, Chuhang Zhou, Yuanhang Zhou, Xinru Li, Yanxia Zhou, Yan Liu
DOI: 10.5246/jcps.2018.07.050
2018 Vol. 27 (7): 490-497 [Abstract] ( 43 ) HTML (78 KB)  PDF (1608 KB)  ( 65 )
498 Acetaminophen-induced hepatotoxicity in rats is correlated with the accumulation of bile acids: an underlying mechanism Hot!
Yongwen Jin, Zhi Rao, Yanfang Wu, Guoqiang Zhang, Axi Shi, Yuhui Wei, Xin’an Wu
DOI: 10.5246/jcps.2018.07.051
2018 Vol. 27 (7): 498-509 [Abstract] ( 41 ) HTML (128 KB)  PDF (1686 KB)  ( 54 )
       Drug administration and clinical pharmacy column
510 Empirical methods in studying the effect of pharmaceutical policies Hot!
Jing Chen, Ting Yin, Bin Jiang
DOI: 10.5246/jcps.2018.07.052
2018 Vol. 27 (7): 510-516 [Abstract] ( 35 ) HTML (76 KB)  PDF (1346 KB)  ( 136 )
  News
· The team of Professor Qiang Zhang has made a series of progress in the field of targeted drug delivery in 2020 new
· Professor Tao Liu secured the Outstanding Youth Science Foundation of Beijing Natural Science Foundation in 2020 new
· Professor Ning Jiao won the Natural Science First Prize of Beijing Science and Technology Award new
· The team of Professor Xinshan Ye has made progress in stereoselective electroglycosylation new
· The group of Yiguang Wang created a new intelligent nano delivery technology in programmed response to tumor molecular signals
· The group of Xinjing Tang developed a novel light-sensitive CRISPR-Cas9 System to realize the light regulation of gene editing
· The group of Suwei Dong created a new strategy to simulate complex polysaccharides using self-assembled peptides
· The group of Prof. Xianrong Qi have provided a new delivery strategy for accurate diagnosis and treatment of glioma
· The group of Prof. Yanxing Jia have realized the first total synthesis of natural product (-)-glaucocalyxin A
· Tao Liu research group of Peking University School of Pharmaceutical Sciences and Mo Li research group of Peking University Third Hospital joint developed CRISPR non-natural amino acid coupling technique to improve the efficiency of precise genome editing
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