Journal of Chinese Pharmaceutical Sciences ›› 2017, Vol. 26 ›› Issue (2): 156-160.DOI: 10.5246/jcps.2017.02.015

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Chemical constituents isolated from the endophytic fungus Penicillium commune

Xintao Chen, Hong Lan, Tao Zheng, Yongcheng Dong, Jun Liang, Chen Li*   

  1. Department of Pharmacy, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, China
  • Received:2016-10-09 Revised:2016-11-25 Online:2017-02-28 Published:2016-12-30
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  • Supported by:

    National Natural Science Foundation of China (Grant Nos. 31370372, 81573316, 31270395, 31570361, and 81202423), the National Science and Technology Project of China (Grant Nos. 2011ZX09102-004 and 2013ZX09103001-020).


Phytochemical investigation of the endophytic fungus Penicillium communeled to the isolation of nine known compounds.Based on the spectroscopic and chemical properties, their structures were identified as 6-acetyl-2α,5-dihydroxy-2-(2-hydroxypropyl)-3α,8-dimethylchroman (1), communol B (2), communol E (3), communol G (4), 2-hydroxy-4-phenylquinoline (5), viridicatol (6), 3-O-methylviridicatin (7), trans-ferulic acid (8), 1,2-benzenediol,4-(2-methoxyethenyl) (9). Compounds 1 and 5-9 were isolated from this fungus for the first time.        

Key words: Penicillium commune, Chemical constituents, Structural identification

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