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Journal of Chinese Pharmaceutical Sciences ›› 2016, Vol. 25 ›› Issue (10): 764-770.DOI: 10.5246/jcps.2016.10.085

• Original articles • Previous Articles     Next Articles

The chemical constituents in the decoction of Urtica fissa rhizomes 

Mengyue Wang, Xiaoru Feng, Chengqin Zhang, Jun Cheng, Enjia Liu, Li'ang Sun, Xiaobo Li*   

  1. School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China
  • Received:2016-06-10 Revised:2016-07-05 Online:2016-10-27 Published:2016-07-15
  • Contact: Tel.: +86-021-34204806, Fax: +86-021-34204804, E-mail: xbli@sjtu.edu.cn
  • Supported by:
    National Natural Science Foundation of China (Grant No. 81374067).

Abstract:

Phytochemical investigation of the decoction of Urtica fissa rhizomes led to the isolation of 23 known compounds. Their structures were identified as medioresinol dimethyl ether (1), L-pyroglutamic acid methyl ester (2), nicotinic acid (3), L-pyroglutamic acid (4), erythritol (5), 6-methyl-2′-deoxy thymidine (6), 2-methyl-6-(2′,3′,4′-trihydroxybutyl)-pyrazine (7), 5-hydroxyl-2-hydroxymethyl pyridine (8) , adenine (9), uracil (10), thymine (11), adenosine (12), inosine (13), 2-deoxyadenosine (14), 2′-deoxyguanosine (15), 2′-deoxyinosine (16), uridine (17), n-butyl-O-β-D-fructopyranoside (18), di-D-fructose (19), β-D-fructofuranosyl-α-D-galactopyranoside (20), bis (5-formyl-furfuryl) ether (21), chlorogenic acid (22), and 5-hydroxymethyl furaldehyde (23) by spectroscopic methods. In addition, a total of 20 compounds (1–20) were isolated from U. fissa for the first time. Meanwhile, compounds 1, 6, 7, 8, 19 and 20 were isolated from the Urticaceae plants for the first time.  

Key words: Urtica fissa, Rhizome, Decoction, Chemical constituents

CLC Number: 

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