Journal of Chinese Pharmaceutical Sciences ›› 2016, Vol. 25 ›› Issue (4): 233-234.

• Editor’s note •     Next Articles

Cancers chemoprevention by dietary phytochemicals and traditional Chinese medicines: epigenetics and cellular signaling pathways

Ah-Ng Tony Kong1, Siwang Yu2   

  1. 1. Department of Pharmaceutics, Earnest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    2. School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China
  • Received:2016-04-01 Revised:2016-04-05 Online:2016-04-21 Published:2016-04-10


The incidence and mortality of cancer have been increasing alarmingly in China and worldwide[1]. Unlike other chronic diseases such as metabolic, cardiovascular, and neuropathies, most cancers, especially metastatic ones, are still essentially uncontrollable in spite of significant progresses such as early diagnosis and immunotherapies. Fortunately, human cancer generally takes about 1030 years to develop; hence there is a window of opportunity to prevent cancer before it becoming metastatic and radio/chemotherapeutic resistant. Indeed, prevention has made huge contribution to cancer control in the United States and some European countries, and chemoprevention is one of the most attractive strategies.

Key words: Cancers chemoprevention, Dietary phytochemicals, Traditional Chinese medicines, Epigenetics, Cellular signaling pathways