• Full Papers • Previous Articles     Next Articles

Isolation and structural elucidation of an unstable isoflavonoid glycoside malonate from Radix hedysari

Yi Liu, Yu-Ying Zhao, Hu-Biao Chen, Qing-Ying Zhang*   

  1. 1. State Key Laboratory of Natural and Biomimetic Drugs; Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China
    2. National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China
    3. School of Chinese Medicine, Hong Kong Baptist University, Hong Kong Special Administrative Region, China
  • Received:2009-11-27 Revised:2010-02-20 Online:2010-03-15 Published:2010-03-15
  • Contact: Qing-Ying Zhang*

Abstract: Based on the stability results of Radix hedysari extract, an unstable compound was extracted using acidic methanol and purified by rapid chromatographic methods successfully from Radix hedysari for the first time guided by HPLC analysis. Its structure was identified as formononetin 7-O-β-D-(6''-O-malonyl)-glucopyranoside by spectroscopic analyses.

Key words: Radix hedysari, Formononetin 7-O-β-D-(6''-O-malonyl)-glucopyranoside, Isoflavonoid glycoside malonate

CLC Number: