Journal of Chinese Pharmaceutical Sciences ›› 2018, Vol. 27 ›› Issue (1): 40-50.DOI: 10.5246/jcps.2018.01.005

• Original articles • Previous Articles     Next Articles

Chemical constituents from the leaves of Cistus parviflorus

Xinyu Fang1, Rongrong Wang1, Shiwei Sun1, Xiaoxiao Liu1, Xiaohong Liu1, Wei Wang1, Yoshihito Okada2, Wei Wang1*   

  1. 1. Department of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 266021, China
    2. Department of Natural Medicine and Phytochemistry, Meiji Pharmaceutical University, Tokyo 204-8588, Japan
  • Received:2017-10-29 Revised:2017-11-12 Online:2018-02-28 Published:2017-11-28
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A phytochemical investigation on the leaves of Cistus parviflorus led to the isolation of 18 compounds. The structures of the isolated compounds were elucidated as kaempferol 3-O-(3′′,6′′-di-O-E-p-coumaroyl)-β-D-glucopyranoside (1), scopoletin (2),kaempferol 3-O-(3′′-O-E-p-coumaroyl)-β-D-glucopyranoside (3), kaempferol 3-O-(6′′-O-E-p-coumaroyl)-β-D-glucopyranoside (4), kaempferol 3-O-β-D-glucopyranoside (5), kaempferol 3-O-α-L-rhamnopyranosyl-(1→2)-(6′′-O-E-p-coumaroyl)-β-D-glucopyranoside (6), methyl flavogallonate(7), quercetin 3-O-β-D-glucopyranoside (8), quercetin 3-O-β-D-galactopyranoside (9), hydroquinone (10), arbutin (11), methyl β-glucopyranoside (12), shikimic acid (13), (S)-1,2-propandiol-1-O-β-D-glucopyranoside (14), benzyl-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (15), 2-phenethyl-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (16), corchoionoside C (17), kaempferol 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (18) by the analysis of the MS and NMR spectroscopic data and comparison with the literature. Compounds 12, 67, 1012, and 1416 were isolated from Cistus genus for the first time. 

Key words: Cistaceae, Cistus parviflorus, Flavonols, Glycosides

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