Journal of Chinese Pharmaceutical Sciences ›› 2016, Vol. 25 ›› Issue (2): 111-115.DOI: 10.5246/jcps.2016.02.011

• 【Original articles】 • Previous Articles     Next Articles

Chemical constituents from Paliurus ramosissimus

Chen Chen1,2, Guandi Luo3, Rong Hu*, Hongzheng Fu2*   

  1. 1. School of Medical Academy, Yangzhou University, Yangzhou 225001, China 
    2. State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing 100191, China
    3. Guangdong Sencee Pharmaceutical Co., Ltd., Jieyang 515500, China
  • Received:2015-10-22 Revised:2015-12-05 Online:2016-02-29 Published:2015-12-15
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  • Supported by:
    National Natural Science Foundation of China (Grant No. 81172943).


In the present research, in order to study the chemical constituents of Paliurus ramosissimus (Lour.) Poir., the isolation of its ingredients was performed by repeated chromatography on silica gel, Sephadex LH-20, ODS and preparative HPLC. Their structures were elucidated on the basis of combination of mass spectrometry and 1D, 2D NMR spectroscopy. A total of 8 compounds were obtained, and their structures were identified as 3β-hydroxy-27-(3,4-dihydroxybenzoyl)oxylup-20(29)-en-28-oic acid(1),betulinic acid (2), lupeol(3), 27-O-trans-caffeoylcylicodiscic acid (4), ceanothic acid (5), 24-hydroxyceanothic acid (6), dihydrokaempferol (7), eriodictyol (8). Among them, compound 1 was a new compound. Compounds 34, 78 were isolated from Paliurus ramosissimus (Lour.) Poir. for the first time.

Key words: Paliurus ramosissimus, Chemical constituents, Structural identification

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